Citation

Basu S, Verma S, Abdin E. Clin. Psychol. Psychother. 2020; ePub(ePub): ePub.

Affiliation

Research Division, Institute of Mental Health, Singapore.

Copyright

(Copyright © 2020, John Wiley and Sons)

DOI

10.1002/cpp.2449

PMID

32196815

Abstract

Depression is commonly seen in the course of Schizophrenia and can occur during any of the phases of the psychotic illness. The present study examines the incidence of depression at baseline and De Novo depression in First episode of non-affective psychoses and the course of depression in the 12 months following first episode psychosis, any predictive significance of baseline depression with recurrence of depression in the subsequent phases of the psychotic illness. The study was conducted with a clinical sample of 460 patients under the care of a First episode psychosis programme and data relating to duration of untreated psychosis, sociodemographic data, PANSS, GAF, CGI was collected. Diagnosis was made by at least two psychiatrists using SCID-1 and depression was measured by PHQ-9. Statistical analysis was performed using SAS version 9. We performed multiple logistic regression analyses to identify the sociodemographic and clinical factors that were associated with depression. Statistical significance was set at p value < 0.05. We found that baseline depression was present in 34.42% patients with a preponderance of females (p =0.047) and in those with secondary education. A suicide attempt is a strong predictor for depression at baseline. There was lower incidence of depression in those diagnosed with Brief Psychotic Disorder (p= 0.015), and those with lower PANSS positive scores, (p = 0.017). De Novo depression over 12 months was 9.44%. Depression at one-year follow-up was significantly predicted by depression at baseline.

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Language: en

Keywords

De Novo depression; Depression; First Episode Psychosis; socio-demographic corelates