Citation

Korley FK, Peacock WF, Eckner JT, Maio R, Levin S, Bechtold KT, Peters M, Roy D, Falk HJ, Hall AJ, Van Meter TE, Gonzalez R, Diaz-Arrastia R. Acad. Emerg. Med. 2019; ePub(ePub): ePub.

Affiliation

Department of Neurology, University of Pennsylvania Perelman School of Medicine, Penn Presbyterian Medical Center, 51 North 39th Street, Philadelphia, PA, 19104.

Copyright

(Copyright © 2019, Society for Academic Emergency Medicine, Publisher John Wiley and Sons)

DOI

10.1111/acem.13844

PMID

31397520

Abstract

There are limited prognostic tools to guide clinicians in acute risk-stratification of adult mild TBI patients (mTBI). While the majority of mTBI patients achieve full recovery within 7-14 days, approximately 25-30% remain symptomatic for 3 or more months post-injury.(1;2) Early identification of the subset of mTBI patients at high risk for protracted recovery will: (a) facilitate administering the right discharge instructions and sub-specialty referral to the right at-risk mTBI patients; (b) enable individualized education of patients regarding their expected course of recovery; (c) allow targeted administration of cognitive and behavioral therapy that has been found to be efficacious when implemented during the acute phase of injury; (3,4,5) and (d) enable enrichment of study populations of mTBI clinical trials with patients who are at-risk for protracted recovery and therefore decrease the sample size required for demonstrating therapeutic efficacy. This article is protected by copyright. All rights reserved.

This article is protected by copyright. All rights reserved.

Language: en