Citation

Vazquez GH, Gonda X, Lolich M, Tondo L, Baldessarini RJ. Harv. Rev. Psychiatry 2018; 26(1): 8-18.

Affiliation

From the Department of Neuroscience, Research Center in Neuroscience and Neuropsychology, Palermo University, Buenos Aires, Argentina (Drs. Vázquez and Lolich); Department of Psychiatry, Queens University, Kingston, Ontario, Canada (Dr. Vázquez); International Consortium for Psychotic & Mood Disorders Research, McLean Hospital, Belmont, MA (Drs. Vázquez, Tondo, and Baldessarini); Department of Psychiatry & Psychotherapy, Kútvölgyi Clinical Center, Semmelweis University, Budapest, Hungary (Dr. Gonda); MTA-SE Neuropsychopharmacology Research Group, Hungarian Academy of Sciences & Semmelweis University, Budapest (Dr. Gonda); Laboratory for Suicide Prevention and Research, National Institute for Psychiatry & Addictology, Budapest (Dr. Gonda); National Council of Scientific & Technical Research (CONICET), Argentina (Dr. Lolich); Department of Psychiatry, Harvard Medical School (Drs. Tondo and Baldessarini); Lucio Bini Mood Disorders Centers, Cagliari & Rome, Italy (Dr. Tondo).

Copyright

(Copyright © 2018, President and Fellows of Harvard College, Publisher Lippincott Williams and Wilkins)

DOI

10.1097/HRP.0000000000000153

PMID

29303918

Abstract

BACKGROUND: Among risk factors for suicidal behavior, there is growing interest in associations with stable affective temperament types, particularly based on assessment with the TEMPS-A self-rating scale.

AIM: As research on this topic has not been reviewed systematically, we synthesized relevant, reported research findings.

METHODS: Systematic searching identified peer-reviewed reports pertaining to associations of suicidal behavior or ideation with affective temperament types evaluated with TEMPS-A. We summarized available findings and applied quantitative meta-analytic methods to compare scale scores in suicidal versus nonsuicidal subjects.

RESULTS: In 21 of 23 TEMPS-A studies meeting inclusion criteria, anxious, cyclothymic, depressive, or irritable temperament scores were significantly higher with previous or recent suicide attempts or ideation in both psychiatric and general population samples compared to nonsuicidal controls, whereas hyperthymic temperament scores were lower in 9 of 11 reports. These findings were synthesized by random-effects meta-analyses of standardized mean differences in TEMPS-A temperament scores in suicidal versus nonsuicidal subjects. Associations ranked: depressive ≥ irritable > cyclothymic > anxious > hyperthymic (negative).

CONCLUSIONS: Affective temperaments, especially depressive and irritable, were strongly associated with suicidal risk, whereas hyperthymic temperament appeared to be protective.

Language: en