Citation

Dunn EL, Cohen RG, Moore EE, Hamstra RD. Arch. Surg. (1960) 1981; 116(8): 1082-1083.

Copyright

(Copyright © 1981, American Medical Association)

DOI

unavailable

PMID

7259514

Abstract

A substantial number of severely injured patients are under the influence of alcohol, making it important to understand the effects of acute alcoholic intoxication on the clotting mechanism. Twenty healthy volunteers ingested commercial liquor over a four-hour period and were observed for another three hours. Peak blood alcohol levels were above 200 mg/dL in four subjects and between 100 and 200 mg/dL in 12. Platelet counts, platelet aggregation, and bleeding times were not significantly altered over the seven hours. This study demonstrates that acute alcoholic intoxication in healthy persons does not alter platelet function.

Language: en