Citation

Vincent AS, Roebuck-Spencer TM, Cernich A. Alzheimers Dement. 2014; 10(3 Suppl): S174-S187.

Affiliation

Mental Health Services, Department of Veterans Affairs, Defense Centers of Excellence for Psychological Health & Traumatic Brain Injury, Washington, DC, USA.

Copyright

(Copyright © 2014, Alzheimer's Association, Publisher Elsevier Publishing)

DOI

10.1016/j.jalz.2014.04.006

PMID

24924669

Abstract

Traumatic brain injury (TBI) is recognized as an important risk factor for the long-term cognitive health of military personnel, particularly in light of growing evidence that TBI increases risk for Alzheimer's disease and other dementias. In this article, we review the neurocognitive and neuropathologic changes after TBI with particular focus on the potential risk for cognitive decline across the life span in military service members. Implications for monitoring and surveillance of cognition in the aging military population are discussed. Additional studies are needed to clarify the factors that increase risk for later life cognitive decline, define the mechanistic link between these factors and dementia, and provide empirically supported interventions to mitigate the impact of TBI on cognition across the life span.

Language: en