Citation

Lavon O, Ben-Zeev A, Bentur Y. Basic Clin. Pharmacol. Toxicol. 2013; 114(3): 288-292.

Affiliation

Israel Information Poison Center, Rambam Health Care Campus, Haifa, Israel; Clinical Pharmacology and Toxicology Unit, Carmel Medical Center, Haifa, Israel.

Copyright

(Copyright © 2013, Nordic Pharmacological Society, Publisher John Wiley and Sons)

DOI

10.1111/bcpt.12150

PMID

24330094

Abstract

Medication errors (ME) are a major concern to healthcare systems. Most studies evaluated ME occurring in healthcare facilities; only few focused on ME outside them. The objective was to characterise ME occurring outside healthcare facilities. A prospective observational follow-up study evaluating all ME occurring outside healthcare facilities reported to a national poison information centre during a 5-month period. For each ME case, a detailed questionnaire was filled and a follow-up call was made within 7 days. The collected data included demographics, circumstances, type of error and outcome. Of 1381 consecutive ME cases were included; 97.8% involved a single incident and 88.3% one drug. The main characteristics of the ME were as follows: children younger than 6 years old (58.9%), parents responsible for 55.6% of cases, wrong dose 34.5% and different medication 30.1%. Analgesics (27.4%) and antimicrobials (12.2%) were the most common pharmaceuticals. The main reasons for the ME were look-alike packaging (31.4%) and misunderstood instructions (28%). Most followed up patients (97.1%) were asymptomatic or mildly affected; there was one severe case and no mortality. Most ME occurring outside healthcare facilities are single incidents, involving young children who were administered a wrong dose or medication due to look-alike packaging or misunderstood instructions with asymptomatic or mild outcome. Improved packaging, labelling and patient education are suggested to reduce ME.

Language: en