Citation

Louise S, Warrington NM, McCaskie PA, Oddy WH, Zubrick SR, Hands B, Mori TA, Briollais L, Silburn S, Palmer LJ, Mattes E, Beilin LJ. Pediatr Obes. 2012; 7(4): 319-328.

Affiliation

Centre for Genetic Epidemiology and Biostatistics, The University of Western Australia, Crawley, Australia.

Copyright

(Copyright © 2012, International Association for the Study of Obesity, Publisher John Wiley and Sons)

DOI

10.1111/j.2047-6310.2012.00047.x

PMID

22511563

Abstract

OBJECTIVE: To examine the influence of aggressive behaviour scores on cardiovascular disease (CVD) risk factors throughout childhood. METHODS: This study utilized cross-sectional and longitudinal data from the Western Australian Pregnancy Cohort (Raine) Study (n = 2900). Aggressive behaviour scores were derived from the Child Behavior Checklist/4-18(CBCL), Youth Self-Report/11-18 (YSR) and Teacher Report Form/6-18 (TRF). CVD risk factors included body mass index (BMI), blood pressure, fasting lipids and homeostasis model of insulin resistance (HOMA-IR). RESULTS: Girls with higher aggressive behaviour scores had higher BMI from 10 years of age (P ≤ 0.001), higher BMI trajectories throughout childhood (P = 0.0003) and at 14 years higher HOMA-IR (P = 0.008). At the 14-year survey, this equated to a difference of 1.7 kg/m(2) in the predicted BMI between the extreme CBCL scores in girls (top 5% (CBCL ≥ 17) vs. CBCL score = 0). Boys with higher aggressive behaviour scores had higher BMI at 5 years (P = 0.002), lower diastolic pressure at 14 years (P = 0.002) and lower systolic blood pressure trajectories throughout childhood (P = 0.016). CONCLUSION: Aggressive behaviour influences BMI from early childhood in girls but not boys. If this association is causal, childhood offers the opportunity for early behavioural intervention for obesity prevention.

Language: en