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Journal Article

Citation

Toomey R, Seidman LJ, Lyons MJ, Faraone SV, Tsuang MT. Schizophr. Res. 1999; 40(2): 121-130.

Affiliation

Harvard Medical School Department of Psychiatry at the Massachusetts Mental Health Center, Boston 02301, USA. rosemary_toomey@hms.harvard.edu

Copyright

(Copyright © 1999, Elsevier Publishing)

DOI

unavailable

PMID

10593452

Abstract

The present study compared nonverbal social perception in relatives of schizophrenic patients (n = 21) with that of normal controls (n= 19). We hypothesized that relatives would display deficits in social perception and we sought to determine the skills that are associated with this deficit. Relatives performed significantly worse than controls on the Profile of Nonverbal Sensitivity Test (PONS), despite comparable performance on skills hypothesized to be related to nonverbal social perception: visual perception, nonverbal problem solving, facial recognition, facial affect recognition, naming, social judgment, and vigilance. To further explore the relationships among these skills, we calculated correlations between the PONS score and associated skills separately within both the relative and control groups and assessed whether the values of these correlations differed between groups. Correlations that differed significantly indicated a greater association, within relatives, between slower reaction times on vigilance tasks and poor PONS performance. Further research is needed to clarify the nature of this relationship, to better characterize social perception deficits in relatives, and to determine whether these perceptual deficits are part of the genetic diathesis to schizophrenia.


Language: en

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