Citation

Douze JM, van Heyst AN, van Dijk A, Maes RA, Drost RH. Arch. Toxicol. 1975; 34(2): 129-136.

Copyright

(Copyright © 1975, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

1242886

Abstract

In three cases of intoxication by Gramoxone¿, the concentration of paraquat dichloride in blood, dialysate, feces, and urine was determined spectrophotometrically after a clean-up of the biological material by means of ion exchange chromatography (with Dowex 50W-X12 or Zeo-Karb 225). Although good results were obtained after clean-up with Dowex 50W-X12, Zeo-Karb was preferred as ion exchange resin, especially when large sample volumes were needed for the determination. The reported findings indicate that: only 5 to 10% of an ingested dose of paraquat dichloride is absorbed in man, Fullers' earth is very useful, and that primary, e.g. immediate, hemodialysis is necessary.

Language: en