Citation

Miller KW. Science 1974; 185(4154): 867-869.

Copyright

(Copyright © 1974, American Association for the Advancement of Science)

DOI

unavailable

PMID

4843793

Abstract

The hypothesis that general anesthesia or pressure-induced convulsions occur when a hydrophobic region is expanded or compressed, respectively, by critical amounts is consistent with recent data obtained with mice. Calculations show that anesthesia occurs at an expansion of 1.1 percent and convulsions at a compression of 0.85 percent, the latter site of action being more compressible.

Language: en