Citation

Sapozhnikova MA, Barinova MV, Mikhaĭlova GV, Evseev AF. Arkh. Patol. 1983; 45(12): 27-36.

Vernacular Title

Patologicheskaia anatomiia travmaticheskogo shoka mirnogo vremeni.

Copyright

(Copyright © 1983, Meditsina)

DOI

unavailable

PMID

6670943

Abstract

The study on the morphology of organs in 316 fatalities due to traumatic shock and blood loss and organs of 120 dogs and 25 rats sacrificed after reproduction of closed trauma of the chest accompanied by blood loss revealed the dependence of morphological changes on the time of shock development and the size of blood loss. Soon after trauma, disorders in the permeability of the capillary basal membrane are found against the background of massive blood loss. Disorders in hemodynamics progress during the first 24 hours when first signs of necrobiosis of the parenchymatous organs begin to appear. Circulatory disorders in the myocardium, brain, and lungs regularly found in this period aggravate the progress of hypoxia and dystrophic changes which are clearly seen in the next 2-4 days. Inadequate treatment in the first days after trauma may increase microcirculatory disorders and necrotic processes sometimes progressing in some organ to its insufficiency, more frequently observed in the lungs or heart (myocardial infarction). The dependence of the above-mentioned complications on the initial manifestations of traumatic shock combined with massive blood loss allowed them to be united into a traumatic disease described in separate phases of its development.

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