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Journal Article

Citation

Rondot P, Bathien N. Encephale (1974) 1979; 5(1): 41-48.

Vernacular Title

Mouvements anormaux induits par les medicaments psychotropes.

Copyright

(Copyright © 1979, Masson Editeur)

DOI

unavailable

PMID

477589

Abstract

The abnormal movements produced by the psychotropic drugs are related to various physiopathological mechanisms: -- dopaminergic receptors blockage provokes neuroleptic parkinsoniam tremor; -- neuroleptic-induced tardive dyskinesia is similar to 1. Dopa abnormal movements; tardive dyskinesia is due to denervation induced hypersensitivity of the dopamine receptor; the 1. Dopa dyskinesia is probably related to altered responsiveness of these receptors due to an increase in dopaminergic receptor sensitivity; -- antidepressant drugs, particularly lithium, provoke tremor, alleviated by beta blockage; it is probably caused by an abnormal sensitivity of the beta noradrenergic receptors.


Language: fr

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