Citation

Dutta AS, Chaudhuri AK. Indian J. Exp. Biol. 1991; 29(10): 937-942.

Affiliation

Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India.

Copyright

(Copyright © 1991, India Publications and Information Directorate)

DOI

unavailable

PMID

1814834

Abstract

Neuropharmacological studies have been conducted on the venom of V. russelli on experimental animals. The venom was found to produce alteration in general behaviour pattern, reduction in spontaneous motility, hypothermia, potentiation of pentobarbitone hypnosis, analgesia, reduction in exploratory behaviour pattern, muscle relaxant action, and suppression of aggressive behaviour. The venom caused a significant increase in brain GABA content in mice. The observations are suggestive of a potent CNS-depressant action of V. russelli venom.

Language: en