Citation

Lidberg L, Dåderman A. Lakartidningen 1997; 94(39): 3385-3388.

Vernacular Title

Nedsatt serotoninhalt predisponerar for vald. Enkelt blodprov forutsager

Affiliation

Sektionen för rättspsykiatri, Karolinska institutet, Stockhom.

Copyright

(Copyright © 1997, Sveriges Lakarforbund)

DOI

unavailable

PMID

9379806

Abstract

Deficient serotonergic function in the brain is associated with a risk of impulsive violence. The level of serotonergic function can be assessed indirectly in several ways: 1. determination of CSF (cerebrospinal fluid) content of the serotonin metabolite 5-HIAA (5-hydroxyindoleacetic acid); 2. determination of the plasma level of the amino acid tryptophan, the serotonin precursor (passage of tryptophan into the brain is dependent on the ratio of tryptophan to other competing amino acids); 3. analysis of platelet monoamine oxidase content, a putative correlate of serotonergic capacity in the brain; 4. by determining response to an OGTT (oral glucose tolerance test), another putative correlate of serotonergic function.

Language: sv