Citation

Liu A, Zhao Q, Guan X. Anal. Chim. Acta 2010; 675(2): 106-115.

Affiliation

Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, TX 76019-0065, USA.

Copyright

(Copyright © 2010, Elsevier Publishing)

DOI

10.1016/j.aca.2010.07.001

PMID

20800721

Abstract

Nanopore stochastic sensor works by monitoring the ionic current modulations induced by the passage of analytes of interest through a single pore, which can be obtained from a biological ion channel by self-assembly or artificially fabricated in a solid-state membrane. In this minireview, we overview the use of biological nanopores and artificial nanopores for the detection of terrorist agents including explosives, organophosphorus nerve agents, nitrogen mustards, organoarsenic compounds, toxins, and viruses. We also discuss the current challenge in the development of deployable nanopore sensors for real-world applications.

Language: en