Citation

Thavundayil JX, Hambalek R, Kin NM, Krishnan B, Lal S. Neuropsychobiology 1994; 30(1): 4-6.

Affiliation

Douglas Hospital Research Centre and Department of Chemistry, Verdun, Canada.

Copyright

(Copyright © 1994, Karger Publishers)

DOI

unavailable

PMID

7969858

Abstract

We describe a subject who developed prolonged penile erections on hydroxyzine. Molecular modelling showed that the hydroxyzine metabolite, norchlorcyclizine, has structural and conformational similarities to the trazodone metabolite, m-chlorophenylpiperazine. This suggests that a common pharmacological mechanism may underlie the ability of trazodone and hydroxyzine to induce erections.

Language: en