Citation

Bickel MH. Schweiz Arch. Neurol. Psychiatr. 1986; 137(5): 106-109.

Vernacular Title

Akute und chronische Toxizitat von Psychopharmaka.

Copyright

(Copyright © 1986, Zeitschriften)

DOI

unavailable

PMID

2431462

Abstract

Within psychotropic drugs acute toxicity is highest in antidepressants (thymoleptics, MAO-inhibitors, lithium), lower in neuroleptics, and very low in anxiolytics. The order of decreasing chronic toxicity is: neuroleptics, antidepressants, anxiolytics. Each class of psychotropic drugs has a specific toxicological problem. With anxiolytics the major problems stem from their misuse and overuse. With neuroleptics tardive dyskinesia is a serious threat to longterm therapy. Finally, antidepressants are characterized by a low therapeutic index and a resulting high incidence of severe and fatal poisoning cases, both intentional and accidental.

Language: de