Citation

Loeber R, Pardini D. Philos. Trans. R. Soc. Lond. B Biol. Sci. 2008; 363(1503): 2491-2503.

Affiliation

University of Pittsburgh Medical Center, Western Psychiatric Hospital and Clinic, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

Copyright

(Copyright © 2008, Royal Society of London)

DOI

10.1098/rstb.2008.0032

PMID

18434284

PMCID

PMC2606713

Abstract

This paper addresses four common assumptions and related controversies regarding neurobiological factors explaining violence: (i) scholars often assume stability of individual differences in neurobiological factors pertaining to violence, yet much change occurs in aggression/violence during the life course, (ii) individual differences in aggression/violence reflect one or more underlying mechanisms that are believed to have neurobiological origins, yet there is little agreement about which underlying mechanisms apply best, (iii) the development of aggression/violence to some degree can be explained by social, individual, economic and environmental factors, yet it is unclear to what extent neurobiological factors can explain the escalation to, and desistance from, violence over and above social, individual, economic and environmental factors, and (iv) violence waxes and wanes in society over time, yet the explanation of secular differences in violence by means of neurobiological and other factors is not clear. Longitudinal analyses from the Pittsburgh Youth Study are used to illustrate several of these issues.

Language: en