Citation

Greenhalgh DG. Adv. Surg. 2024; 58(1): 1-17.

Copyright

(Copyright © 2024, Elsevier Publishing)

DOI

10.1016/j.yasu.2024.04.001

PMID

39089770

Abstract

The optimal treatment of burn shock is still unresolved. The problem of "fluid creep" continues despite modern devices that fail to improve outcomes over hourly urine output. Colloids, especially albumin, reduce fluid requirements. Albumin can be used either immediately at the start of resuscitation, or as a "rescue" when crystalloid use is excessive. Several studies confirm that when crystalloid resuscitation is "out of control" the majority of caregivers will add albumin to reduce fluid rates. A multi-center trial is underway comparing crystalloids with albumin to confirm the benefit of colloids. The next question is whether albumin or plasma is as the better colloid choice.

Language: en

Keywords

Humans; Resuscitation; Burns; *Burns/therapy; *Albumins/therapeutic use/administration & dosage; *Fluid Therapy/methods; *Resuscitation/methods; Albumin; Colloid; Colloids/therapeutic use/administration & dosage; Crystalloid; Crystalloid Solutions/administration & dosage/therapeutic use; Endothelium; Glycocalyx; Isotonic Solutions/therapeutic use/administration & dosage