Citation

De Buck R. Acta Psychiatr. Belg. 1978; 78(5): 841-854.

Copyright

(Copyright © 1978, Acta Psychiatrica Belgica)

DOI

unavailable

PMID

unavailable

Abstract

It has been shown in a clinical trial that mianserin induces a hypomania in some manic-depressed patients. Regarding its antidepressive effect, mianserin is superior to placebo and as effective as imipramine and amitriptyline. It works simultaneously on anxiety, psychomotor retardation, and suicidal tendency; sleep improves under mianserin's influence. The value of mianserin is proven by its safety and lack of side effects. (English, Dutch, German, Italian, & Spanish summaries) (35 ref) (PsycINFO Database Record (c) 2016 APA, all rights reserved)

Keywords

Animals; Antidepressant Drugs; antidepressant effects of mianserin; Antidepressive Agents, Tricyclic; Bipolar Disorder; Clinical Trials as Topic; Depression; Depression (Emotion); Dibenzazepines; Drug Evaluation; Drugs; Heart; Humans; Mianserin; Norepinephrine; Psychiatric Status Rating Scales; Psychopharmacology; Serotonin Antagonists; Sleep; Suicide