Citation

Lu PH, Tseng JC, Chen CK, Chen CH. J. Clin. Pharm. Ther. 2017; 42(4): 506-508.

Copyright

(Copyright © 2017, John Wiley and Sons)

DOI

10.1111/jcpt.12538

PMID

28547870

Abstract

WHAT IS KNOWN AND OBJECTIVE: Massive acute arsenic poisoning is rare yet potentially life-threatening. 2,3-dimercaptopropane-1-sulphonate (DMPS) appears to have the appropriate chelating property. However, clinical experience on the use of DMPS in massive arsenic poisoning is limited.
CASE DESCRIPTION: A 37-year-old woman attempted suicide by ingesting 37.5 g of arsenic trioxide. DMPS was promptly initiated based on history and clinical symptoms. The patient recovered completely, with no complications or side effects of the therapy.
WHAT IS NEW AND CONCLUSION: TDMPS is useful for the treatment of massive acute arsenic poisoning.

Language: en

Keywords

Humans; Adult; Female; Treatment Outcome; Suicide, Attempted; arsenic; arsenic poisoning; chelation therapy; Chelating Agents; Arsenicals; Arsenic Poisoning; Oxides; Arsenic Trioxide; Peripheral Nervous System Diseases; Unithiol; 2,3-dimercaptopropane-1-sulphonate