Citation

Veras AB, Cougo S, Meira F, Peixoto C, Barros JA, Nardi AE, Malaspina D, Poyurovsky M, Kahn JP. Psychiatry Res. 2017; 257: 172-178.

Copyright

(Copyright © 2017, Elsevier Publishing)

DOI

10.1016/j.psychres.2017.07.048

PMID

28763736

Abstract

Twenty patients with DSM5 schizophrenia were comprehensively and formally assessed by an experienced psychiatrist. All subjects were assessed for: positive and negative psychotic symptoms; social anxiety; panic anxiety; obsessive compulsive disorder, atypical depression; major depression; suicide risk; and global assessment of functioning. Different profiles of clinical presentation and symptom evolution emerged for patients with schizophrenia who had co-morbid depression (15%), OCD (15%), panic or limited symptom attacks (55%) and social anxiety (5%). At least eighty percent of the sample had one or more of these co-morbidities. Summing up, the data support our previous finding that panic is highly prevalent in Schizophrenia with Auditory Hallucinations (>73% here, versus 100% before), and panic was paroxysmally concurrent with voice onset. Moreover, characteristic clinical findings may help point clinicians to five specific co-morbidity psychosis subtypes. Moreover, co-morbidity dissection of psychotic diagnoses recalls and parallels the historical psychopharmacologic dissection of non-psychotic anxiety and depressive subtypes diagnoses. Larger studies should further test and explore these preliminary findings.

Language: en

Keywords

Humans; Adult; Female; Male; Middle Aged; Retrospective Studies; Psychiatry; Comorbidity; Pilot Projects; Prevalence; Schizophrenia; Anxiety Disorders; Schizophrenic Psychology; Psychotic Disorders; Melancholia; OCD; Obsessive-Compulsive Disorder; Evolution; Panic; Depressive Disorder, Major; Hallucinations; Panic Disorder; Social Anxiety; Atypical Depression