Citation

Prescrire Int. 2016; 25(175): e234.

Copyright

(Copyright © 2016, Association Mieux Prescrire)

DOI

unavailable

PMID

30645825

Abstract

In a placebo-controlled trial in 374 men, prucalopride was only effective in a minority of cases, as previously observed in women. In addition to its cardiovascular harms, there is evidence that prucalopride may cause depression and suicidal ideation.

Language: en

Keywords

Humans; Female; Male; Depression; Risk Assessment; Cardiovascular Diseases; Treatment Outcome; Suicidal Ideation; Chronic Disease; Constipation; Laxatives; Benzofurans; Controlled Clinical Trials as Topic; Contraindications, Drug; Defecation; Serotonin 5-HT4 Receptor Agonists