Citation

Tsai CH, Cheng WJ, Muo CH, Lin TL. Medicine (Baltimore) 2019; 98(3): e14148.

Copyright

(Copyright © 2019, Lippincott Williams and Wilkins)

DOI

10.1097/MD.0000000000014148

PMID

30653150

PMCID

PMC6370150

Abstract

This study aimed to evaluate the association between fracture history and sequential risk of suicidal behavior.A total of 82,804 patients with fractures and 82,804 control subjects without fractures were matched. The influence of fractures on the risk of suicidal behavior-related hospital visit was analyzed using a Cox proportional hazards model.The overall adjusted hazard ratio (aHR) of suicidal behavior-related hospital visit was 2.21 in fracture cohort. The aHR declined from 2.90 at the 1-year follow-up to 2.00 after 5 years or more. In fracture patients, the risk of suicidal behavior-related hospital visit was higher at age <35 years, with comorbidities of stroke and sleep disorder. Patients with multiple fractures had a 1.69-fold risk.Fractures are an independent risk factor for suicidal behavior. Individuals aged younger than 35 years, with comorbidities of stroke and sleep disorder, and those who have suffered multiple fractures have elevated risk of suicidal behavior among subjects in the fracture group. Furthermore, this increased risk remained even after 5 years had passed since the fracture incident.

Language: en

Keywords

Humans; Risk Factors; Adult; Female; Male; Middle Aged; Retrospective Studies; Risk Assessment; Hospitalization; Cohort Studies; Proportional Hazards Models; Suicidal Ideation; Databases, Factual; Taiwan; Fractures, Bone