Citation

Teti Mayer J, Chopard G, Nicolier M, Gabriel D, Masse C, Giustiniani J, Vandel P, Haffen E, Bennabi D. Prog. Neuropsychopharmacol. Biol. Psychiatry 2020; 98: e109814.

Copyright

(Copyright © 2020, Elsevier Publishing)

DOI

10.1016/j.pnpbp.2019.109814

PMID

31715284

Abstract

Impulsivity is a multidimensional phenomenon that remains hard to define. It compounds the core pathological construct of many neuropsychiatric illnesses, and despite its close relation to suicide risk, it currently has no specific treatment. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique whose application results in cognitive function improvement, both in healthy and psychiatric populations. Following PRISMA recommendations, a systematic review of the literature concerning tDCS's effects on impulsive behaviour was performed using the PubMed database. The research was based on the combination of the keyword 'tDCS' with 'impulsivity', 'response inhibition', 'risk-taking', 'planning', 'delay discounting' or 'craving'. The initial search yielded 309 articles, 92 of which were included. Seventy-four papers demonstrated improvement in task performance related to impulsivity in both healthy and clinical adult populations. However, results were often inconsistent. The conditions associated with improvement, such as tDCS parameters and other aspects that may influence tDCS's outcomes, are discussed. The overall effects of tDCS on impulsivity are promising. Yet further research is required to develop a more comprehensive understanding of impulsivity, allowing for a more accurate assessment of its behavioural outcomes as well as a definition of tDCS therapeutic protocols for impulsive disorders.

Language: en

Keywords

Humans; Risk-Taking; Impulsivity; Impulsive Behavior; Dorsolateral prefrontal cortex; Craving; Psychiatric disorders; Disruptive, Impulse Control, and Conduct Disorders; Transcranial Direct Current Stimulation; Inhibition, Psychological; Delay Discounting; Healthy subjects; Transcranial direct current stimulation