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Journal Article

Citation

Occhipinti S, Zajdlewicz L, Coughlin GD, Yaxley JW, Dunglison N, Gardiner RA, Chambers SK. Psychooncology 2019; 28(12): 2389-2395.

Copyright

(Copyright © 2019, John Wiley and Sons)

DOI

10.1002/pon.5263

PMID

31659807

Abstract

BACKGROUND: Men treated for prostate cancer experience heightened psychological distress and have an increased risk of suicide. Management of this distress and risk is crucial for quality urological care.
OBJECTIVE: To identify risk indicators for poorer trajectories of psychological adjustment and health-related quality of life (QoL) after surgery for localised prostate cancer.
DESIGN, SETTING, AND PARTICIPANTS: Patients were newly diagnosed with localised prostate cancer scheduled for surgical treatment. Patients were assessed at baseline (pre-surgery) and 6 weeks, 3 months, 6 months, 12 months, and 24 months post-surgery.
MEASUREMENTS: Assessment measures included sociodemographics, domain-specific and health-related QoL, and psychological distress. Mixed effects regression models were used to analyse the data.
RESULTS AND LIMITATIONS: A total of 233 patients provided data for this analysis (Mage = 60 years, standard deviation [SD] = 4.02; MPSA = 7.37 ng/mL). At baseline, the prevalence of high psychological distress was 28% reducing to 21% at 24 months. Before treatment, younger age, more comorbidities, and worse bowel function were related to greater psychological distress; and younger age and better urinary, sexual, and bowel function were related to better health-related QoL. By contrast, for changes over time, only bowel function was important with better bowel function predicting decreasing psychological distress for men.
CONCLUSIONS: Regular distress screening is indicated over the 24 months after surgery for localised prostate cancer. Care pathways for men with prostate cancer need also to respond to age-specific concerns and health problems associated with comorbidities in aging men. Focussed symptom control for bowel bother should be a priority.


Language: en

Keywords

Humans; Risk Factors; Aged; Male; Middle Aged; Prospective Studies; quality of life; Longitudinal Studies; Quality of Life; Adaptation, Psychological; prostate cancer; Prostatic Neoplasms; Psychological Distress; Emotional Adjustment; Prostatectomy; distress, longitudinal; oncology, prostatectomy

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