Citation

Dulaurent S, Gaulier JM, Zouaoui K, Moesch C, François B, Lachâtre G. Forensic Sci. Int. 2011; 212(1-3): e10-14.

Copyright

(Copyright © 2011, Elsevier Publishing)

DOI

10.1016/j.forsciint.2011.05.011

PMID

21640530

Abstract

We present two non fatal cases of intoxication with carbofuran (CBF) documented by hair analysis. Carbofuran and 3-hydroxycarbofuran (OHCBF, its main metabolite) hair concentrations were determined using a liquid chromatography-tandem mass spectrometry method. The obtained results were surprising if we consider several hair analyses previously published and based on a theory of the presence of xenobiotic in the only segment that comprised its intake. Among the two intoxication cases, we noticed the presence of CBF and OHCBF in hair segments corresponding to 45 days before, and more than 100 days after, the day of intoxication. Additionally, repeated hair samplings and subsequent analysis revealed a decrease of the carbofuran's concentration during the hair life.

Language: en

Keywords

Humans; Male; Middle Aged; Risk Assessment; Time Factors; Suicide, Attempted; France; Follow-Up Studies; Forensic Toxicology; Insecticides; Hair; Gas Chromatography-Mass Spectrometry; Carbofuran