Citation

Mula M, Jauch R, Cavanna A, Collimedaglia L, Barbagli D, Gaus V, Kretz R, Viana M, Cantello R, Monaco F, Schmitz B. Seizure 2009; 18(7): 530-532.

Copyright

(Copyright © 2009, Elsevier Publishing)

DOI

10.1016/j.seizure.2009.05.008

PMID

19541505

Abstract

PURPOSE: Although several studies pointed out an association between depression and quality of life (QoL) of patients with epilepsy, data about manic/hypomanic symptoms (MHS) remain scanty. In this study, we sought to investigate their relationship with social and health-related QoL measures in patients with epilepsy.
METHODS: Consecutive adult outpatients with epilepsy were assessed using the M.I.N.I. Plus version 5.0.0 and the QOLIE-31.
RESULTS: Among 117 evaluated patients, 17 fulfilled DSM-IV criteria for manic/hypomanic episodes. Patients with MHS, as compared to those without, showed lower scores in emotional well-being, energy and fatigue, medication effects, social function and total QOLIE score. However, there was no between-groups difference in educational achievements, employment status, living situation, comorbid psychiatric disorders, history of suicide or abuse of illicit drugs.
CONCLUSIONS: MHS are associated with poor QoL measures in patients with epilepsy, though without differences in educational achievements, employment status and independent living.

Language: en

Keywords

Adult; Bipolar Disorder; Comorbidity; Employment; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Personality Inventory; Psychiatric Status Rating Scales; Severity of Illness Index; Socioeconomic Factors; Surveys and Questionnaires