Citation

Shprecher DR, Flanigan KM, Smith AG, Smith SM, Schenkenberg T, Steffens J. J. Neuropsychiatry Clin. Neurosci. 2008; 20(4): 473-477.

Copyright

(Copyright © 2008, American Neuropsychiatric Association, Publisher American Psychiatric Publishing)

DOI

10.1176/jnp.2008.20.4.473

PMID

19196933

Abstract

Delayed hypoxic leukoencephalopathy is an underrecognized syndrome of delayed demyelination, which is important to consider when delayed onset of neuropsychiatric symptoms follows a hypoxic event. The authors describe clinical and diagnostic features of three such cases, review the pathophysiology of delayed hypoxic leukoencephalopathy, and discuss features which may help distinguish it from toxic leukoencephalopathy.

Language: en

Keywords

Adult; Analgesics, Opioid; Benzodiazepines; Brain; Cocaine; Cognition Disorders; Depressive Disorder, Major; Drug Overdose; Female; Fentanyl; Fibromyalgia; Gait Disorders, Neurologic; Humans; Hypoxia, Brain; Magnetic Resonance Imaging; Methadone; Middle Aged; Motor Neurons; Narcotic Antagonists; Neuropsychological Tests; Psychoses, Substance-Induced; Suicide, Attempted