Citation

Kpade C, Durieu I, Limodin J, Paulin M, Magni C, Lemaire JF. Rev. Neurol. (Masson) 2004; 160(5 Pt 1): 568-570.

Copyright

(Copyright © 2004, Elsevier Publishing)

DOI

10.1016/s0035-3787(04)70988-1

PMID

15269676

Abstract

Arising via an unidentified pathogenic mechanism, central pontine myelinolysis affects the central portion of the base of the pons. Rapid correction of hyponatremia is a frequent cause. The main symptoms are spastic tetraparesis, pseudobulbar paralysis and locked-in syndrome. We report a case of central pontine myelinolysis without hyponatremia, revealed by left upper monoplegia in a 40-Year-old female alcoholic patient without malnutrition symptom. Central pontine myelinolysis occurred consecutive to a suicide attempt with multiple drugs and alcohol. The diagnosis was confirmed by brain magnetic resonance imaging. This case illustrates the paucisymptomatic clinical characteristics of central ponine myelinolysis in patients without electrolyte and nutritional disorders.

Language: fr

Keywords

Adult; Alcoholism; Arm; Female; Functional Laterality; Humans; Hyponatremia; Magnetic Resonance Imaging; Myelinolysis, Central Pontine; Paralysis; Suicide, Attempted