Citation

Westrin A, Niméus A. Eur. Psychiatry 2003; 18(4): 166-171.

Copyright

(Copyright © 2003, Elsevier Publishing)

DOI

10.1016/s0924-9338(03)00044-0

PMID

12814849

Abstract

This study tested suicidality in relation to cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5-HIAA) and the dexamethasone suppression test. Patients with nonsuppression of cortisol had the highest scores of the Suicide Assessment Scale (SUAS) and the Montgomery Asberg Depression Rating Scale (MADRS), respectively (P < 0.05; P < 0.01). The results persisted when analysed for covariance with CSF-5-HIAA. We have previously noted an elevated suicide risk in suicide attempters with high SUAS-scores, why a large part of nonsuppressors may be at high risk for future suicide.

Language: en

Keywords

Adult; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Middle Aged; Personality Inventory; Predictive Value of Tests; Risk; Suicide; Suicide Prevention; Suicide, Attempted