Citation

Himmerich H, Szegedi A, Klawe C, Anghelescu I, Müller MJ. Eur. Psychiatry 2003; 18(6): 318-319.

Copyright

(Copyright © 2003, Elsevier Publishing)

DOI

10.1016/j.eurpsy.2002.11.001

PMID

14611928

Abstract

A female patient with multiple sclerosis (MS) suffered from an acute psychotic disorder after taking distigmine bromide for detrusor dysfunction. She showed a dramatic relief of her symptoms after the medication, distigmine bromide, was stopped. Distigmine is not supposed to penetrate the blood-brain barrier (BBB). However, in MS patients a leakage of the BBB could be hypothesized.

Language: en

Keywords

Female; Humans; Male; Multiple Sclerosis; Parasympathomimetics; Psychiatric Status Rating Scales; Psychoses, Substance-Induced; Pyridinium Compounds; Suicide, Attempted; Urinary Retention