Citation

Lalonde FM, Myslobodsky M. Breast (Edinburgh, Scotland) 2003; 12(4): 280-282.

Copyright

(Copyright © 2003)

DOI

10.1016/s0960-9776(03)00061-4

PMID

14659314

Abstract

Women undergoing chemotherapy for breast cancer are often administered dopamine antagonist adjuvant medications that may increase levels of prolactin potentially increasing the risk of cancer. Using nationwide computerized registers of death data for the years 1991 through 1996 we examined 12,430,473 deaths of persons over 40 years of age and extracted 144,364 cases with Parkinson's disease (PD), a dopamine deficient population. Patients with PD had lower rates of breast and other types of malignancies, even in the presence of depression and suicide.

Language: en

Keywords

Adult; Age Distribution; Aged; Aged, 80 and over; Antipsychotic Agents; Breast Neoplasms; Dopamine Antagonists; Female; Follow-Up Studies; Humans; Incidence; Middle Aged; Parkinson Disease; Prolactin; Psychotic Disorders; Registries; Retrospective Studies; Risk Assessment; United States