Citation

Zurawski JM, Kelly EA. Obstet. Gynecol. 1997; 90(4 Pt 2): 672-674.

Copyright

(Copyright © 1997, Lippincott Williams & Wilkins)

DOI

10.1016/s0029-7844(97)00408-0

PMID

11770591

Abstract

BACKGROUND: Brodifacoum is a potent warfarin-like anticoagulant used in many rat-poisoning products. Its availability has led to several reported human ingestions, none previously reported in pregnancy.
CASE: A woman presented at 22 weeks' gestation in hemorrhagic diathesis, attributed to the ingestion of rat poison containing brodifacoum several days earlier. Aggressive vitamin K therapy controlled the maternal coagulopathy, and no fetal hemorrhage was observed by sonography. Her subsequent prenatal course and delivery were unremarkable, and she was delivered of a healthy infant, who has remained well for at least 1 year.
CONCLUSION: In this patient, brodifacoum ingestion in pregnancy caused substantial maternal hemorrhage, but no fetal hemorrhage or teratogenic effects were observed.

Language: en

Keywords

4-Hydroxycoumarins; Adult; Female; Humans; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Rodenticides; Suicide, Attempted