Citation

Wang J, Chen X, Lou F. Zhonghua Yi Xue Za Zhi 2000; 80(4): 275-277.

Copyright

(Copyright © 2000, Zhonghua yi xue hui)

DOI

unavailable

PMID

11798771

Abstract

OBJECTIVE: To investigate P300 and contingent negative variations (CNV) of patients with affective disorder and its clinical significance.
METHODS: 39 depressives, 22 maniacs and 33 normal controls were included in this study. Both P300 and CNV were recorded in every subject, using a nicolet spirit instrument.
RESULTS: Both depression and mania groups presented prolonged P300-P3b latency and decreased P300-P3 and CNV amplitudes compared with normal controls. Decreased P300 & CNV amplitudes were further related to the history of suicide behavior in the two patient groups.
CONCLUSION: The clinical significance of event-related potentials was confirmed in this study, while the biological correlates of suicide behavior need further and intensive study.

Language: zh

Keywords

Adult; Affective Disorders, Psychotic; Bipolar Disorder; Contingent Negative Variation; Depression; Event-Related Potentials, P300; Female; Humans; Male; Predictive Value of Tests; Suicide