Citation

Herrero JL, Castellano I, Gómez-Martino JR, Novillo R, Covarsí A. Nefrologia 2001; 21(6): 592-595.

Copyright

(Copyright © 2001, Sociedad Espanola de Nefrologia)

DOI

unavailable

PMID

11881430

Abstract

Paracetamol poisoning is manifested by hepatotoxicity, but acute renal failure is very rare, especially when there is no fulminant hepatic damage with encephalopathy or severe haemodynamic alterations. We present here the case of a 22-year-old woman who presented with acute renal failure after the ingestion of 11.5 g of acetaminophen. The clinical course and laboratory data were consistent with tubular necrosis. The patient required hemodialysis, but finally renal function returned to normal. The acetaminophen pharmacology and the differential diagnosis of acute azotemia in paracetamol overdosage are reviewed.

Language: es

Keywords

Acetaminophen; Acute Kidney Injury; Adult; Blood Coagulation Tests; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Humans; Kidney Function Tests; Kidney Tubular Necrosis, Acute; Liver Function Tests; Nausea; Renal Dialysis; Suicide, Attempted; Vomiting