Citation

Armitage R. Can. J. Psychiatry 2000; 45(9): 803-809.

Copyright

(Copyright © 2000, Canadian Psychiatric Association, Publisher SAGE Publications)

DOI

10.1177/070674370004500903

PMID

11143829

Abstract

This paper reviews sleep disturbances in patients with major depressive disorders and the effects of different classes of antidepressants on sleep. It is clear from the studies reviewed that not all antidepressants improve sleep, and, indeed, some worsen sleep disturbances in patients with depression. Whether sleep is improved or further disrupted is of high clinical significance, because persistent sleep problems elevate the risk of relapse, recurrence, or suicide, as well as the need for augmenting medications.

Language: en

Keywords

Antidepressive Agents; Depressive Disorder, Major; Humans; Sleep Stages; Sleep Wake Disorders