Citation

de Haro L, Valli M, Bourdon JH, Iliadis A, Hayek-Lanthois M, Arditti J. Vet. Hum. Toxico. 2001; 43(3): 174-175.

Copyright

(Copyright © 2001, American College of Veterinary Toxicologists)

DOI

unavailable

PMID

11383664

Abstract

A 54-y-old man ingested 2 g of bulk laboratory diazepam and was treated with activated charcoal, enhanced diuresis and flumazenil infusion. The treatment resulted in awakening, but the patient had drowsiness, dysarthria, diplopia, and dizziness for 9 d. Blood levels of diazepam and its main metabolite, nordiazepam, were obtained for 1 mo. The half-lives in this benzodiazepine overdose were longer than those seen with therapeutic doses. Benzodiazepines should not be readministrated when patients awake after suicide attempts.

Language: en

Keywords

Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Diazepam; Flumazenil; Humans; Male; Middle Aged; Nordazepam; Poisoning; Suicide, Attempted; Treatment Outcome