|
Abstract
|
OBJECTIVE: To determine the rate of complications of ileoanal pouch anastomosis, their treatment and their influence on a successful outcome.
DESIGN: A computerized database and chart review.
SETTING: Three academic tertiary care health centres.
PATIENTS: All 239 patients admitted for surgery between 1981 and 1994 with a diagnosis of ulcerative colitis and familial adenomatosis coli.
INTERVENTIONS: Sphincter-saving total proctocolectomy and construction of either S-type of J-type ileoanal reservoir.
OUTCOME MEASURES: Indications, early and late complications, incidence of pouch excision.
RESULTS: Of the 239 patients, 228 (95.4%) were operated on for ulcerative colitis and 11 (4.6%) for familial polyposis coli. One patient in each group was found to have a carcinoma not previously diagnosed. Twenty-eight patients had poor results: in 17 (7.1%) the ileostomy was never closed or was re-established because of pelvic sepsis or complex fistulas, sclerosing cholangitis or severe diarrhea; 11 (4.6%) patients required excision of the pouch because of anal stenosis, perirectal abscess-fistula or rectovaginal fistula. Three patients died--of suicide, and complications of liver transplantation and HIV infection. Thus, 208 patients maintained a functioning pouch. The early complication rate (within 30 days of operation) was 57.7% (138 patients) and the late complication rate was 52.3% (125 patients). Pouchitis alone did not lead to failure or pouch excision. Emptying difficulties in 25 patients with anal stenosis were helped in 2 by resorting to intermittent catheterization. Patients with indeterminate colitis had a higher rate of anorectal septic complications, and all patients having Crohn's disease after pouch construction had complicated courses.
CONCLUSIONS: The complication rate associated with ileoanal pouch anastomosis continues to be relatively high despite increasing experience with this technique. Overall, however, a satisfactory outcome was obtained in 87% of patients.
Language: en |
|
Keywords
|
Abscess; Adenomatous Polyposis Coli; Adult; Anal Canal; Anus Diseases; Cause of Death; Cholangitis, Sclerosing; Colitis, Ulcerative; Constriction, Pathologic; Crohn Disease; Diarrhea; Female; Follow-Up Studies; Humans; Ileostomy; Incidence; Male; Pelvis; Pouchitis; Proctocolectomy, Restorative; Rectal Diseases; Rectal Fistula; Rectovaginal Fistula; Reoperation; Retrospective Studies; Treatment Outcome |