Citation

Davenport A. Am. J. Kidney Dis. 1998; 32(4): E3.

Copyright

(Copyright © 1998, National Kidney Foundation, Publisher Elsevier Publishing)

DOI

10.1016/s0272-6386(98)70041-1

PMID

10074589

Abstract

Heparin-associated thrombocytopenia occurred in a patient during continuous renal replacement therapy (CRRT), resulting in repeated clotting of the extracorporeal circuit and spontaneous hemorrhage. The peripheral platelet count initially appeared to improve by changing to prostacyclin and dalteparin. However, repeated CRRT circuit clotting recurred, and the platelet count decreased once again. This time the synthetic heparinoid, Orgaran (danaparoid), was used and was associated with successful CRRT and return of the platelet count.

Language: en

Keywords

Adult; Anticoagulants; Chondroitin Sulfates; Dermatan Sulfate; Female; Heparin; Heparitin Sulfate; Humans; Kidney; Multiple Trauma; Platelet Count; Pregnancy; Recurrence; Renal Replacement Therapy; Rupture; Suicide, Attempted; Thrombocytopenia