Citation

Springfield AC, Bodiford E. J. Anal. Toxicol. 1996; 20(3): 202-203.

Copyright

(Copyright © 1996, Preston Publications)

DOI

10.1093/jat/20.3.202

PMID

8735204

Abstract

A fatality resulting from the suicidal ingestion of risperidone is described. The decedent had a lengthy history of mental illness but was otherwise healthy. Biological fluid samples obtained at autopsy were analyzed for risperidone by high-performance liquid chromatography. The blood concentration of risperidone was 1.8 mg/L, the urine concentration was 14.4 mg/L, and the concentration in the gastric contents was 34.6 mg/L (1.04 mg total). The 9-hydroxy-risperidone metabolite was not detected in the blood or gastric contents; however, the urine contained 17.8 mg/L of this metabolite.

Language: en

Keywords

Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Overdose; Fatal Outcome; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Humans; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Reference Standards; Risperidone; Suicide