Citation

Clarke DD. Neurochem. Res. 1991; 16(9): 1055-1058.

Copyright

(Copyright © 1991, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/BF00965850

PMID

1784332

Abstract

The concept of lethal synthesis as suggested by Peters is reviewed in the light of the more recent work in this area. It is suggested that fluorocitrate is a "suicide" substrate for aconitase rather than a competitive inhibitor as originally suggested. The use of these substances to study glial-neuronal relationships is considered.

Language: en

Keywords

Aconitate Hydratase; Animals; Citrates; Fluoroacetates; Neuroglia; Neurons