Citation

Grewal RP. Int. J. Psychiatry Med. 1993; 23(3): 307-312.

Copyright

(Copyright © 1993, SAGE Publishing)

DOI

10.2190/JKFW-3WXK-QA7N-BYLN

PMID

8270359

Abstract

OBJECTIVE: To determine the frequency and etiology of psychiatric complications in patients with Fabry's disease.

METHOD-Retrospective analysis and review of the records of thirty-three patients with confirmed Fabry's disease.
RESULTS: Six patients (18%) developed psychiatric disorders. Five patients suffered depression and two of these patients committed suicide. One patient developed an acute confusional episode with subsequent development of behavioral changes as a complication of cerebrovascular disease.
CONCLUSIONS: Psychiatric disorders, most commonly depression, complicate Fabry's disease and contribute to the morbidity and mortality of this disease.

Language: en

Keywords

Adult; alpha-Galactosidase; Carbamazepine; Cerebrovascular Disorders; Diplopia; Fabry Disease; Humans; Male; Mental Disorders; Pain