Citation

Brouwer CB, Lerk P, Tjoeng MM, van der Hoven B, Bartelink AKM. Clin. Intensive Care 1994; 5(1): 37-39.

Copyright

(Copyright © 1994, Informa - Taylor and Francis Group)

DOI

unavailable

PMID

unavailable

Abstract

A 43-year-old woman with a history of alcohol abuse presented with coma and myoclonic contractions. Two hours before admission she had ingested about 200 ml of 70% (w/v) isopropanol. Gas chromatography showed a serum isopropanol concentration of 2.8 g/l. Nine hours after ingestion the isopropanol level had fallen to 1.4 g/l, but acetone had increased from 0.32 to 1.3 g/l. Haemodialysis rapidly eliminated isopropanol thus preventing further conversion to acetone. Consciousness was regained and the patient recovered fully. Haemodialysis is considered beneficial in shortening the symptoms of isopropanol intoxication and in preventing the accumulation of the toxic metabolite acetone.

Language: en

Keywords

adult; human; female; Poisoning; case report; hemodialysis; suicide attempt; intoxication; alcohol abuse; article; clinical feature; coma; myoclonus; gas chromatography; blood level; Coma; Acetone; 2 propanol; acetone; Isopropyl alcohol