Citation

Hillman DC, Siffre M, Milano G, Halberg F. New Trends Exp. Clin. Psychiatry 1994; 10(4): 173-178.

Copyright

(Copyright © 1994, CIC edizioni internazionali)

DOI

unavailable

PMID

unavailable

Abstract

Infradian components, with a frequency lower than 1 cycle in 28 hours, in the time structures (chronomes) of several physiologic variables are recorded in a woman isolated from society for 103 days in a cave. The physiologic time series rendered equidistant by editing reveal a phase-modulated 73-hour periodicity over much of the isolation span in the inter-micturition interval and in the urinary water excretion rate. The caffeine metabolite ratio also reveals a circasemiseptan. Rather than interpreting this circasemiseptan free-run as purely endogenous, a coherence with cosmic ray disturbance at a trial period not differentiated from precisely 84 hours is noted from cross-spectral analyses. Later suicide, depression in 2 earlier isolation cases, and earlier associations of ward behavior with cosmic rays add both a biophysical and a psychiatric context to these findings.

Language: en

Keywords

adult; human; female; depression; caffeine; social isolation; circadian rhythm; article; normal human; human experiment; micturition; circasemiseptan; cosmic radiation; cosmic rays; endogenous; free-running; synchronization