Citation

Rose JE, Leeson PD, Gani D. Journal of the Chemical Society, Chemical Communications 1992; (24): 1784-1786.

Copyright

(Copyright © 1992)

DOI

10.1039/C39920001784

PMID

unavailable

Abstract

E. coli glutamic acid decarboxylase is inactivated by both enantiomers of the suicide inhibitor serine O-sulfate, inactivation by the (2S)-enantiomer involving Cα-H bond cleavage and inactivation by the (2R)-isomer involving Cα-decarboxylation; both processes occur on the 4′-Re-face of the coenzyme, the opposite face to that utilised in the physiological decarboxylation reaction.

Language: en