Citation

Arango V, Mann JJ. Int. Rev. Psychiatry 1992; 4(2): 131-140.

Copyright

(Copyright © 1992, Informa - Taylor and Francis Group)

DOI

10.3109/09540269209066310

PMID

unavailable

Abstract

This is a review of postmortem studies in the brain of suicide victims. The main focus is on the serotonergic system, looking at both pre-and postsynaptic indices. It includes studies which measured the levels of serotonin and its metabolite 5-hydroxyindole acetic acid, as well as studies of serotonin 5-HT1A and 5-HT2 receptors, and the serotonin transporter. Reports on other transmitter systems are also included, as is a comparison of violent versus nonviolent deaths, depression and postmortem interval. © 1992 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

Language: en

Keywords

human; brain; autopsy; depression; suicidal behavior; review; serotonin; 5 hydroxyindoleacetic acid; neurotransmission; neuropathology; serotoninergic system; serotonin 1a receptor; serotonin 2 receptor