Citation

Sein Anand, Korolkiewicz PK, Sein Anand J. Int. J. Occup. Med. Environ. Health 2021; 34(1): 133-138.

Copyright

(Copyright © 2021, Nofer Institute of Occupational Medicine, Lodz and the Polish Association of Occupational Medicine, Publisher Walter de Gruyter)

DOI

10.13075/ijomeh.1896.01629

PMID

33223540

Abstract

Morphine is an opiate alkaloid characterized by various clinical effects, among which the most prominent are its analgesic and psychoactive effects. It also has a prominent depressive effect on the respiratory and cardiovascular system. Because of its psychoactive effect, morphine is very addictive and often used as a recreational narcotic. As a medication, it has found its use as an analgesic agent in chronic pain treatment, in hemorrhagic shock, and in acute heart failure with pulmonary edema. Albeit, morphine use in heart failure is controversial, based on many observational studies showing the negative effect on the outcomes of the patients treated with morphine during acute cardiovascular incidents. In this report, the authors present a case of cardiogenic shock (CS) with transient left ventricular ejection fraction reduction, occurring in a patient attempting suicide using a high dose of intravenous morphine sulphate administration. Other CS causes were ruled out. To the best of the authors' knowledge, this is the second case of a morphine-related CS reported in literature. Int J Occup Med Environ Health. 2021;34(1):133-8.

Language: en

Keywords

Administration, Intravenous; Adult; Analgesics, Opioid; cardiogenic shock; Humans; Hypotension; Male; morphine; Morphine; Naloxone; Narcotic Antagonists; Norepinephrine; opioids; pharmacology; Shock, Cardiogenic; suicide; Suicide, Attempted; toxicology; Ventricular Dysfunction, Left; Ventricular Function, Left