Citation

Sergentanis I, Vibert V, Costanza A, de Néris M, Besson M, Kosel M, Bondolfi G, Ambrosetti J. Rev. Med. Suisse 2021; 17(725): 303-306.

Copyright

(Copyright © 2021, Medecine et Hygiene)

DOI

unavailable

PMID

33586375

Abstract

Ketamine and its S-enantiomer, esketamine, have shown to be promising molecules for use in psychiatry. Widely investigated for the treatment of drug-resistant depression, they could be used in emergency conditions, due to their rapid onset of action, in two main conditions : 1) psychomotor agitation, and 2) acute suicidal ideation and behavior (suicidal crisis). In particular, intranasal administration offers a non-invasive, safe and very easy to administer option. An effect begins a few hours to a day after intake and lasts for about a week. These molecules present an innovative option for the future and their specific use in psychiatric emergencies.

Language: fr

Keywords

Humans; Suicidal Ideation; Antidepressive Agents; Ketamine; Emergencies; Administration, Intranasal