Citation

Ferry T, Amiet V, Natterer J, Perez MH, Pfister R, Colombier S, Longchamp D. Scand. J. Trauma Resusc. Emerg. Med. 2021; 29(1): e48.

Copyright

(Copyright © 2021, Scandinavian Networking Group on Trauma and Emergency Management, Publisher Holtzbrinck Springer Nature Publishing Group - BMC)

DOI

10.1186/s13049-021-00850-0

PMID

33722251

PMCID

PMC7958095

Abstract

BACKGROUND: Chloroquine use has increased worldwide recently in the setting of experimental treatment for the novel coronavirus disease (Covid-19). Nevertheless, in case of chloroquine intoxication, it can be life threatening, with cardiac arrest, due to its cardiac toxicity.
CASE PRESENTATION: This case study reports on a 14-years-old girl who presented in cardiac arrest after an uncommon suicide attempt by ingesting 3 g of chloroquine. After 66 min of cardio-pulmonary resuscitation (CPR), extracorporeal cardiopulmonary resuscitation (ECPR) was initiated, allowing cardiac function to recover.
CONCLUSIONS: Chloroquine intoxication is a rare but serious condition due to its cardiac toxicity. Use of ECPR in this case of transient toxicity allowed a favorable evolution with little neurological impairment.

Language: en

Keywords

Humans; Female; Adolescent; Severity of Illness Index; COVID-19; Heart Arrest; Resuscitation; Pediatrics; Cardiopulmonary Resuscitation; Extracorporeal Membrane Oxygenation; Emergency medicine; Chloroquine; Arrhythmia; SARS-CoV-2; Pandemics; Intensive Care; COVID-19 Drug Treatment; Antimalarials; Extracorporeal Life support